Albumin/Globulin Ratio Calculator

Divide albumin by globulin. If your lab report only shows total protein and albumin, first estimate globulin as total protein minus albumin, then divide: A/G ratio equals albumin divided by the quantity total protein minus albumin. For example, albumin 4.0 g/dL and total protein 7.0 g/dL give globulin 3.0 g/dL and an A/G ratio of 4.0 divided by 3.0, which is about 1.333.

Commonly quoted reference ranges include 1.0 to 2.0, 1.1 to 2.5, and 1.5 to 2.5, and different laboratories use different ranges depending on their assay method and population. This calculator lets you pick the range your own lab uses before interpreting the result. Always compare against the reference range printed on your lab report.

A ratio below the reference range means globulin is high relative to albumin, or albumin is low relative to globulin. Clinicians sometimes encounter this pattern with chronic inflammation or autoimmune conditions, liver conditions that lower albumin production, or kidney conditions with protein loss in urine. It is an educational observation, not a diagnosis; the cause is determined from the full clinical picture.

A ratio above the reference range means globulin is low relative to albumin, or albumin is relatively high. Clinicians sometimes encounter this pattern with low immunoglobulin levels or with dehydration, which concentrates blood proteins. A high ratio is the least common abnormal direction and is interpreted in clinical context, not on its own.

Globulin is estimated as total protein minus albumin. Lab reports usually measure total protein and albumin directly; the remaining protein fraction is reported as globulin. This calculator shows that intermediate step so you can check it against your own report.

Typical adult reference values often cited are albumin 3.5 to 5.0 g/dL, total protein 6.0 to 8.3 g/dL, and globulin 2.0 to 3.5 g/dL, but exact ranges vary by laboratory. In g/L these are ten times larger: albumin 35 to 50 g/L, total protein 60 to 83 g/L. Use the reference range on your own report for interpretation.

Both g/dL and g/L are supported. One g/dL equals ten g/L, so you can convert either way and the calculator converts your inputs to a common unit before calculating. The A/G ratio itself has no units because the units cancel in the division.

No. This calculator performs the arithmetic on your lab values and adds educational context about how clinicians view the ratio. It does not diagnose, rule out, or predict any condition, and it cannot replace a qualified healthcare professional, who interprets the ratio together with your albumin and globulin values, other tests, symptoms, and history.

Use the inverse solver in this calculator. Algebraically, with ratio R and total protein T, albumin equals R times T divided by R plus 1, and globulin equals T divided by R plus 1. For example, a ratio of 1.333 with total protein 7.0 g/dL gives albumin about 4.0 g/dL and globulin about 3.0 g/dL.

Reference ranges depend on the assay method, the instruments and reagents used, and the population the lab studied when setting its ranges. That is why one source quotes 1.0 to 2.0 and another quotes 1.5 to 2.5. Interpret your result against the range printed on your own lab report, which reflects the method that produced your numbers.

It depends on the reference range in use. With a range of 1.0 to 2.0, a value exactly on the boundary is inside the usual range; with a range of 1.1 to 2.5, a ratio of 1.0 falls below it. Boundaries are conventions of the chosen range, not hard biological cutoffs, so select your lab's range in the calculator and discuss borderline values with your clinician.

They are different tests. The A/G ratio compares two protein fractions in blood serum and is calculated from albumin and total protein. The albumin-creatinine ratio is measured in urine and screens for kidney damage. If you need the urine test, see the albumin-creatinine ratio information on our kidney failure risk page, not this calculator.